Mode of regulation of natural killer cell activity by interferon
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Mode of regulation of natural killer cell activity by interferon
Whereas xenogeneic tumors such as baby hamster kidney or HeLa cells grow in nude mice, the same cells persistently infected with a variety of viruses are rejected. Spleen cells from normal nude mice were found to be induced to produce interferon and to exert natural killer (NK) activity on virus persistently infected (PI) tumor cells, and not on uninfected parental cells in vitro. The phenotype...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1980
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.152.1.124